Detangle electric comb: can it cure baldness? What the study found

An electric comb called Detangle regrew almost all lost hair in balding mice within a month. Pakistanis are searching it, but it is not a product you can buy.

A hand holding the clear Detangle electric comb with electrode teeth
Image: ZME Science

“Detangle electric comb” is one of the top Google searches in Pakistan today, after reports that scientists have built a comb that regrew nearly all the lost hair on balding mice in about a month. The short answer for anyone with thinning hair: it is a lab experiment, tested only in mice, and you cannot buy it.

What is the Detangle comb?

It was built by researchers at Beihang University in Beijing and described in the journal Nature Communications, Medical Xpress and New Atlas reported. Instead of plain bristles, its “teeth” are electrodes of different heights with small built-in modules that hold medicine.

When it is combed over the scalp, a gentle electric field helps push the medicine into the cells of the hair follicles, which is normally very hard to do through skin. The team used two molecules: one (a VEGFA plasmid) that encourages blood vessel growth around follicles, and one (an SRD5A2 siRNA) aimed at the enzyme behind male-pattern baldness, the same pathway the tablet finasteride targets.

What did it do in mice?

In balding mice, the comb restored hair across almost all of the treated patch within a month, doing better than minoxidil in the same experiment, Medical Xpress reported. ZME Science put the minoxidil group at around 70% regrowth against near-complete regrowth with Detangle. One report said it also beat finasteride, and no skin damage was seen.

So is baldness cured?

Not yet. Every report stresses this is preclinical. Mouse hair grows and cycles very differently from human hair, and many treatments that work in mice never reach clinics. No human trial has been reported. Even if trials start, it would take years of testing before any regulator could approve it.

Why Pakistanis are searching it

Hair loss is a huge worry here, from young men losing hair in their twenties to women dealing with thinning after pregnancy, and the market is full of oils, serums and “laser combs” sold on Instagram and Daraz. Expect sellers to use this news. Any “electric comb” sold online today is not the Detangle device from this study.

If you are losing hair, a dermatologist can check the cause (genes, thyroid, iron, stress) and tell you which proven treatments suit you.

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